Melasma, or the 'pregnancy mask', is characterized by pigmentation spots in the face as a result of an excess of pigment (melanin) in the skin. In melasma, erratic light brown to dark brown spots appear on the forehead, cheekbone or upper lip. A harmless skin condition with a major impact on your appearance. Do you find it increasingly difficult to camouflage the stains? Do you want to prevent the spots from getting worse? Stop walking around with pigmentation spots! Make an appointment to reduce these spots.


Melasma has a chronic character: once contracted, your skin remains sensitive to it, especially during the sunny periods of the year. Melasma can appear suddenly and gradually spread, but it can also disappear on its own. Melasma can often be recognized by the irregularly shaped discolorations.

These light brown to dark brown spots develop gradually through sun exposure in combination with the hormones estrogen and progesterone that stimulate the production of melanin (pigment). In response to this hormonal increase, the pigment cells release more pigment. The number of pigment cells in the epidermis is basically normal in people with melasma. During pregnancy, the production of various hormones in the body is increased. Oral contraceptives can also trigger melasma. Hereditary susceptibility often plays a role as well.

Aggressive treatments only provide a temporary effect or eventual aggravation of the spots. Therefore be critical by who and how you are being treated.

At Skin Project we are specialized in treating melasma. We have searched for a long time for a safe and effective method of treatment against melasma. With the Cosmelan we finally found the best way. With an intensive process we help you to make your skin more even, so that you get a calmer skin image.

Home products

The treatment plan is always twofold. In addition to the treatments that we perform in practice, it is also essential that you get started with the recommended exfoliating products for home (at least 2 to 4 weeks before the first treatment). By using the exfoliating products at home, the dead skin cells are removed and the skin thins. As a result, the skin becomes more permeable and the Cosmelan peeling reaches the deeper layers of the skin better, so that the most optimal result is achieved faster and the treatment is more effective. The skin will also recover faster after a treatment and the results of the treatment will be maintained for longer, so that maintenance treatments are needed less often.


The most effective and safe way to remove melasma and excessive pigmentation from dark skin is treatment with Cosmelan. The Cosmelan treatment from Mesoestetic is THE number 1 worldwide depigmentation treatment and suitable for all skin types.

Cosmelan works in two parts. The first part includes treatment in the clinic. A mask is applied here during the treatment, which works very intensively on your pigment. The second part involves the use of home products (included in the price). These products continue the action to address the disruption in the pigment. By sticking to the advice, you reduce the chance of the pigment coming back.

Cosmelan inhibits the production of pigment. In addition, the Cosmelan mask contains the following ingredients: kojic acid, phytic acid, ascorbic acid, arbutin, titanium dioxin and retinyl palmitate (vitamin A type), all of which block the enzyme tyrosinase. All products are perfume free.

How does the treatment proceed?

Preparation: to properly prepare the skin for the Cosmelan mask, it is important that the skin is prepared at home with the recommended acids. The acids ensure that the dead skin cells are removed from the skin, allowing the Cosmelan mask to work better and reducing the risk of side effects.

Pre-peeling: 2 days before applying the Cosmelan mask, it is recommended to first apply a Pre-peeling to allow the skin to get used to the acids and to increase the skin's permeability, allowing the Cosmelan 1 mask to penetrate deeper into the skin. coming.

Cosmelan mask: in practice, half of the jar of the Cosmelan 1 mask will be applied by the skin therapist. This mask will stay on the skin for 8-12 hours. You will go home with this mask and you will need to remove the mask from the skin yourself after the elapsed time.

After 2 days: you get a call appointment for a check. Then you will start with the other products such as Cosmelan 2 cream, Melan Recovery cream and the SPF130 for home. You will receive detailed instructions for this

After 2 weeks: Will we schedule another appointment to apply the Cosmelan 1 again (the other half of the jar). It has proven to be more effective to schedule this in 2 separate appointments.

Follow-up: we will schedule a checkup appointment 3 times (after every month) in 3 months so that we can keep track of the result. At home, on the advice of the skin therapist, you continue with the home products that are included in the price. Follow-up checks are also included in the price.

What effect can you expect?

After the mask (applied in the clinic) the skin is red and feels burning and tight. This is normal, especially during the first 24-48 hours after starting treatment. To reduce this, use the supplied Melan Recovery cream. Flaking occurs on the second or third day in all skin types. It is advisable to use the Melan recovery cream and to repeat this every two hours if the flaking is very bad. A week after the treatment, the skin starts to improve! In 95% of cases, the best result is achieved between 1-4 weeks. The pigmentation will be significantly reduced, or even disappear.

To prevent and/or reduce the return of spots, it is very important to continue to take good care of the skin at home after the treatment. It is essential to continue to use good and high sun protection (SPF50).

It is also recommended to continue using the Cosmelan 2 in the evening for up to a year after the treatment to maintain the result.

Important to know

The trajectory consists of treatments in the clinic, skin products for the home and changes in how you deal with sunlight.

Melasma is a skin condition with which more and more people know where to find us. It is a challenging request for help, because melasma is not easy to treat. Fortunately, we have the expertise to help you safely with this annoying skin condition. The Cosmelan trajectory is an intensive trajectory. The way in which you deal with sunlight also determines the maintenance of the treatment results. Honest and transparent information is very important to us at Skin Project. That is why we always tell our clients: daylight is sunlight, the best anti-pigment cream is at least an SPF 50 daily! Prevention is better than cure. Make sure you maintain the results achieved by protecting your skin every day all year round.


When even deeper pigments are present after the Cosmelan treatment, you can switch to the Dermamelan treatment. The Dermamelan is 30% stronger than a Cosmelan treatment. And thereby penetrates deeper into the skin to tackle the most stubborn pigment problems at the core.

Reimbursement health insurance

Treatment for pigmentation spots in the face can possibly be reimbursed under camouflage therapy from the additional health insurance. Skin Project is recognized by all health insurers.

Over melasma

What Causes Melasma?

The exact cause of melasma is still unknown. It is clear that there is a hypersensitivity in the pigment cells to daylight, artificial UV radiation, blue light and sometimes heat. Inducing factors of this hypersensitivity are: pregnancy, contraception, some anti-epileptic drugs, hereditary predisposition and certain cosmetics with, for example, perfume.

What is the difference between pigmentation spots and melasma?

Melasma is a chronic skin condition in which the skin has a permanent sensitivity to producing too much melanin due to hormones. Fortunately, there are more and more treatment options to treat this stubborn skin condition. Where pigmentation spots are relatively easy to treat, melasma is more of a challenge.

Can melasma treatment be reimbursed?

There are some health insurers that also reimburse the pigment treatments. These treatments are used to reduce or remove pigmentation spots in the face.

What is the main trigger?

The main trigger of melasma is sunlight. This stimulates your pigment cell to make pigment. In the case of melasma, this is hypersensitive, so that your pigment cell produces even more melanin (pigment). Without sunlight you will not get pigmentation spots. New scientific research even shows that screen light (blue light) and with skin type III and above, heat (such as during a sauna visit) stimulate your pigment cells to produce extra melanin.

Do I need a referral letter?

No, a referral is not necessary. Skin therapy is directly accessible. Anyone who wants to work on beautiful skin is welcome.

Why do I choose Skin Project?

You will be treated by experienced BIG-registered hbo-trained skin therapists. You can achieve healthy skin with the right knowledge, scientifically substantiated methods and (medical) equipment, proven medical techniques and the right home advice. We therefore only have the very best in house for both medical and cosmetic skin care. The quality of the treatment is paramount to make you healthier, more beautiful and above all happier. You are always central to our clinic and you are not a number.

Make an appointment without obligation

Are you bothered by the erratic pigment spots on your forehead, cheekbones or upper lip and are you insecure about this? Do you want beautiful skin without pigmentation spots? Come by for a free and non-binding consultation with one of our skin therapists. During the consultation we are happy to give you appropriate and personal treatment advice.

The right products for home

In addition to the treatments and to maintain the skin well at home, we recommend these products!

1.Night Cream






View all our products here